Calendario›TCRT›Ad-RTS-hIL-12
Ad-RTS-hIL-12
Evaluation of Ad-RTS-hIL-12 + Veledimex in Subjects With Recurrent or Progressive Glioblastoma, a Substudy to ATI001-102
Ensayo de Alaunos Therapeutics, Inc. en Glioblastoma.
Más ensayos de: Glioblastoma.
- Fase
- Fase 1
- Estado
- Completado
- Participantes
- 36
- Centros
- 4
- Fin del objetivo primario
- abr 2019
Qué significa cada fase y cada estado.
Estudio de intervención, de un solo grupo, abierto. Comenzó en sep 2018.
Qué mide
Safety of Intratumoral Ad-RTS-hIL-12 and Oral Veledimex in Subjects With Recurrent or Progressive Glioblastoma Based on Evaluation of Adverse Events Summarized by Incidence, Intensity and Type of Adverse Event. (From the first dose of study treatment until 30 days after the last dose of veledimex, lasting approximately 5 months.) (del registro, en inglés)
Cómo lo describe el promotor
En el documentoEn inglés, del registroThis research study involves an investigational product: Ad-RTS-hIL-12 given with veledimex for production of human IL-12. IL-12 is a protein that can improve the body's natural response to disease by enhancing the ability of the immune system to kill tumor cells and may interfere with blood flow to the tumor. The main purpose of this study is to evaluate the safety and tolerability of a single intratumoral injection of Ad-RTS-hIL-12 given with oral veledimex.
Más ensayos de TCRT
| Ensayo | Fase | Estado | Lectura de resultados |
|---|---|---|---|
| Neoantigen specific TCR-T cell… | no aplica | Completado | may 2025 (real) |
| HLA Typing & Tumor Neoantigen Identification for Phase I/II Study of Autologous TCR-T Cells in Subjects With Solid Tumors | no aplica | Interrumpido | ago 2023 (real) |
| Neoantigen specific TCR-T cell… | Fase 1/2 | Interrumpido | ago 2023 (real) |
| Ad-RTS-hIL-12 | Fase 1/2 | Interrumpido | sep 2021 (real) |
| Ad-RTS-hIL-12 | Fase 2 | Interrumpido | ago 2021 (real) |
| Ad-RTS-hIL-12 | Fase 1 | Completado | oct 2020 (real) |
Todos los de TCRT, en su ficha.
Ficha completa en ClinicalTrials.gov (NCT03679754), actualizada en ago 2025.